'Virus-cracking' molecules advance fight
against hepatitis B
It is estimated that about 2 billion people in
worldwide are affected with hepatitis B virus infection in their lifetime and
it is the most trending infection in world wide. Although there is a vaccine
for this infection but there is no cure. A new drug has developed that depends
on how the morphology of the hepatitis B virus changes when bound to an
experimental drug.
The discovery suggests that these drugs could attack
hepatitis B virus on multiple fronts that is both preventing replication and
killing new copies of the virus. This drug can be use in multiple ways that can
work at the same time. Generally, a virus reproduces by takeover a host’s
cellular machinery and produces more of the virus. Most viruses protect their
genetic material - DNA or RNA inside a protein shell called as
"capsid." But recently a class of molecules called core protein
allosteric modulators or CpAMs has discovered that disturb capsid protein
assembly.
CpAM molecules attack viruses by causing their shells
to assemble incorrectly, interrupting the life cycle of the virus. Previously,
CpAMs were only able to disrupt a virus during formation of the capsid; as a
result its DNA was protected inside a hard casing. But this study finds that
the molecules can break this capsid because of which the further replication of
the virus is not possible.
For this discovery, scientists bound the CpAM to a
chemical called TAMRA, a crimson coloured dye used in some red lipstick to make
it fluorescent and easier to detect in experiments. Using cryo-electron
microscopy, they found that a small CpAM molecule could make the large, soccer
ball-shaped virus capsid bend and distort. This is a most effective research to
fight against hepatitis B infection that is helpful for the society.
Annual Conference on Bacterial, Viral and Infectious
Diseases scheduled during August 06-08, 2018 in Abu Dhabi, UAE will provide an
open field of discussion on Hepatitis B virus by distinguished scientists and
how to diminish the infection rate. It also provides opportunities to the young
researchers to network with eminent researchers in the field improving career
opportunities.
My name is hoover, my 18 year old daughter, Tricia was diagnosed with herpes 3 years ago. Since then, we have moved from one hospital to another. We tried all kinds of pills, but every effort to get rid of the virus was futile. The bubbles continued to reappear after a few months. My daughter was using 200mg acyclovir pills. 2 tablets every 6 hours and 15g of fusitin cream. and H5 POT. Permanganate with water to be applied twice a day, but all still do not show results. So, I was on the internet a few months ago, to look for other ways to save my only son. Only then did I come across a comment about the herbal treatment of Dr Imoloa and decided to give it a try. I contacted him and he prepared some herbs and sent them, along with guidance on how to use them via the DHL courier service. my daughter used it as directed by dr imoloa and in less than 14 days, my daughter recovered her health. You should contact dr imoloa today directly at his email address for any type of health problem; lupus disease, mouth ulcer, mouth cancer, body pain, fever, hepatitis ABC, syphilis, diarrhea, HIV / AIDS, Huntington's disease, back acne, chronic kidney failure, addison's disease, chronic pain, Crohn's pain, cystic fibrosis, fibromyalgia, inflammatory Bowel disease, fungal nail disease, Lyme disease, Celia disease, Lymphoma, Major depression, Malignant melanoma, Mania, Melorheostosis, Meniere's disease, Mucopolysaccharidosis, Multiple sclerosis, Muscular dystrophy, Rheumatoid arthritis Alzheimer's disease, parkinson's disease, vaginal cancer, epilepsy Anxiety Disorders, Autoimmune Disease, Back Pain, Back Sprain, Bipolar Disorder, Brain Tumor, Malignant, Bruxism, Bulimia, Cervical Disc Disease, Cardiovascular Disease, Neoplasms , chronic respiratory disease, mental and behavioral disorder, Cystic Fibrosis, Hypertension, Diabetes, Asthma, Autoimmune inflammatory media arthritis ed. chronic kidney disease, inflammatory joint disease, impotence, alcohol spectrum feta, dysthymic disorder, eczema, tuberculosis, chronic fatigue syndrome, constipation, inflammatory bowel disease. and many more; contact him at drimolaherbalmademedicine@gmail.com./ also with whatssap- + 2347081986098.
ReplyDelete